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demonstrated that inhibition of core fucosylation attenuates IGF-1-induced activation of PI3K/Akt signaling, reduces alveolar epithelial cell senescence, and alleviates pulmonary fibrosis, thereby providing direct evidence linking fucosylation to senescence through this signaling axis in the lung [60]

It may seem farfetched that disease in the lungs can lead to disease in the gut, but a new study from scientists at South Koreas Kyung Hee University shows that these two regions are more connected than you might realize